A 44-year old man was referred to our hospital because of right hemianopsia for three months. Physical examination was unremarkable except for left leg amputation because of trauma backed to last year. Laboratory studies including WBC count, BUN, creatinine, liver function test, ECG and chest x ray were normal.

Metastatic involvement of cardiac Valve and pericardium mimicking a cardiac Valve pathology accompanied with cardiac tamponade is a rare phenomenon. These metastases commonly arise from the lymphoreticular system, the pulmonary system, and breast. Metastatic spread of breast carcinoma to the cardiac Valve is exceedingly rare, and only two case reports have been detected in English literature so far. We report a rare case of a patient with adenocarcinoma of the breast, which presented with severe Mitral Valve regurgitation and pericardial effusion which was managed urgently with Mitral Valve replacement. Our case shows the probability of combined metastatic pericardial and Valve involvement in patients with breast adenocarcinoma. The patient was treated with Mitral Valve replacement and intrapericardial infusion of cisplatinum drug to control possible recurrent effusion.

Infective endocarditis (IE) is lethal complications inspite of advanced antibiotics. Prosthetic Valve endocarditis (PVE) complications are dehiscence, paravalvular leak, perivalvular abscess, heart failure, persistent fever, positive blood culture and presence of vegetation. Therefore, the diagnosis is confirmed by clinical findings, blood cultures, and echo data according to Duke’, s criteria. Surgery in those cases are life-saving when indicated, despite it carries high risk mortality especially after stroke.

Myxoma is the most common type of primary tumors of the heart. It is a rare tumor with an estimated incidence of 0.5 per million populations per year. Most cardiac myxomas originate in the atrial septum in the area of the fossa ovalis and 75% occur in the left atrium. Valvular myxomas are very rare: the tricuspid Valve is the most frequently involved location, followed by the Mitral, pulmonic, and aortic Valves.Our case was a 24-year-old male with Mitral Valve myxoma and a history of progressive dyspnea.After diagnosis was confirmed by 2-dimensional echocardiography, he underwent cardiac surgery, the tumor was successfully excised from the posterior leaflet of the Mitral Valve, and the Mitral Valve defect was repaired with direct suture.  

Primary heart tumors are not common. Although myxoma is the most common tumor of the heart, Mitral Valve myxoma is extremely rare. The patient is a 55 years old woman who had atypical retrosternal pain, retinal artery emboli and visual deficit. In transesophageal echocardiography a (4x3x3) cm mass was detected in posterior leaflet of Mitral Valve. The posterior leaflet of Mitral Valve was totally resected and the Mitral Valve was successfully replaced with prosthetic mechanical Valve. Histopathology result confirmed myxoma.